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Benefits Of PRP For Shoulder and Knee Pain: A New Age of Pain Relief In 2025 

Aches in important, load-bearing joints like the shoulder and the knee can render you incapacitated. Thus, patients with chronic pain spend millions of dollars and countless hours visiting doctors. Fortunately, we now have therapies that can turn your life around by alleviating ages-old pain. Platelet-rich plasma, or PRP, is a field of healthcare that is revolutionising pain-management therapies. PRP injections have proven to be highly effective for various pain disorders of the shoulder and knee. Thus, we highlight the therapy’s role in reducing pain. 

How Does PRP Work? 

PRP therapy is famous for boosting your inner healing capabilities. It’s not your regular pain-killer analgesic or an anti-inflammatory steroid that externally curbs down the pain and inflammation; instead, it is something that strengthens your body so that it itself fights the causes of pain. Plasma injections in the affected area load the region with important proteins and growth factors that amp up the healing process. Moreover, it stimulates the production of cells that protect your joints, for example, collagen in osteoarthritis.  

PRP For Shoulder Pain  

Healthcare workers frequently employ PRP injections in the treatment of various shoulder pathologies. A 2023 study advocates the use of PRP for shoulder pain disorders like frozen shoulder (adhesive capsulitis) and rotator cuff repair. Intra-articular PRP injection therapy (in conjunction with other modalities) is a potent new strategy in the management of frozen shoulder. Adhesive capsulitis patients across the globe have noted reductions in pain, improvement in range of motion, and a significant reduction in disability after PRP injections. 

PRP therapy can prove to be extremely effective in other debilitating shoulder pain disorders, including, i.e., rotator cuff tendinitis. Systematic analyses reveal that PRP injection is a highly effective and safe intervention for rotator cuff disorders that provides long-term relief. 

PRP For Knee Pain  

Knee osteoarthritis is a highly prevalent inflammatory disorder having a global prevalence of 16%. Patients encountering knee pain have poor life qualities and have a hard time performing the basic tasks of the day. PRP has been proven to be better than any other injectable treatment option. Newer studies show that higher platelet PRP provides superior results and more durable functional improvement. What sets it apart from other treatments is better and longer (sustained) pain relief with the power to reduce disease progression. It works wonderfully well for other knee pain disorders as well. 

Best PRP In The Villages 

It’s a proven fact that PRP therapy is a safe and effective treatment for knee and shoulder pathologies. But you need to have a trained professional to ensure safety and maximum efficacy. Residents of The Villages, Florida, have the option to get PRP for shoulder and knee pain from the best professionals. The Legacy Clinic of Chiropractic has been a center of pain relief for individuals with knee pain and shoulder pain. Our facility not only provides health care but also makes sure to tailor the treatment according to your needs. So, don’t let shoulder and knee pain get the best of you! Click here for an appointment. 

References  

  1. Rosso, C., Morrey, M. E., Schär, M. O., & Grezda, K. (2023). The role of platelet-rich plasma in shoulder pathologies: a critical review of the literature. EFORT Open Reviews, 8(4), 213-222. 
  2. Harna, B., Gupta, V., Arya, S., Jeyaraman, N., Rajendran, R. L., Jeyaraman, M., … & Ahn, B. C. (2022). Current role of intra-articular injections of platelet-rich plasma in adhesive capsulitis of shoulder: a systematic review. Bioengineering, 10(1), 21. 
  3. Lin, H. W., Tam, K. W., Liou, T. H., Rau, C. L., Huang, S. W., & Hsu, T. H. (2023). Efficacy of platelet-rich plasma injection on range of motion, pain, and disability in patients with adhesive capsulitis: a systematic review and meta-analysis. Archives of Physical Medicine and Rehabilitation, 104(12), 2109-2122. 
  4. A. Hamid, M. S., & Sazlina, S. G. (2021). Platelet-rich plasma for rotator cuff tendinopathy: A systematic review and meta-analysis. Plos one, 16(5), e0251111. 
  5. Cui, A., Li, H., Wang, D., Zhong, J., Chen, Y., & Lu, H. (2020). Global, regional prevalence, incidence and risk factors of knee osteoarthritis in population-based studies. EClinicalMedicine, 29. 
  6. Filardo, G., Previtali, D., Napoli, F., Candrian, C., Zaffagnini, S., & Grassi, A. (2021). PRP injections for the treatment of knee osteoarthritis: a meta-analysis of randomized controlled trials. Cartilage, 13(1_suppl), 364S-375S. 
  7. Bensa, A., Previtali, D., Sangiorgio, A., Boffa, A., Salerno, M., & Filardo, G. (2025). PRP injections for the treatment of knee osteoarthritis: The improvement is clinically significant and influenced by platelet concentration: A meta-analysis of randomized controlled trials. The American Journal of Sports Medicine, 53(3), 745-754. 
  8. Khalid, S., Ali, A., Deepak, F. N. U., Zulfiqar, M. S., Malik, L. U., Fouzan, Z., … & Bhattarai, P. (2024). Comparative effectiveness of intra-articular therapies in knee osteoarthritis: a meta-analysis comparing platelet-rich plasma (PRP) with other treatment modalities. Annals of Medicine and Surgery, 86(1), 361-372.